Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong
Identifieur interne : 005416 ( Main/Exploration ); précédent : 005415; suivant : 005417Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong
Auteurs : Tze-Wai Wong [République populaire de Chine] ; Chin-Kei Lee [Australie] ; Wilson Tam [République populaire de Chine] ; Joseph Tak-Fai Lau [République populaire de Chine] ; Tak-Sun Yu [République populaire de Chine] ; Siu-Fai Lui [République populaire de Chine] ; Paul K. S. Chan [République populaire de Chine] ; Yuguo Li [République populaire de Chine] ; Joseph S. Bresee [États-Unis] ; Joseph J. Y. Sung [République populaire de Chine] ; Umesh D. Parashar [États-Unis]Source :
- Emerging Infectious Diseases [ 1080-6040 ] ; 2004.
Abstract
We studied transmission patterns of severe acute respiratory syndrome (SARS) among medical students exposed exclusively to the first SARS patient in the Prince of Wales Hospital in Hong Kong, before his illness was recognized. We conducted a retrospective cohort study of 66 medical students who visited the index patient’s ward, including 16 students with SARS and 50 healthy students. The risk of contracting SARS was sevenfold greater among students who definitely visited the index case’s cubicle than in those who did not (10/27 [41%] versus 1/20 [5%], relative risk [RR] 7.4; 95% confidence interval [CI] 1.0 to 53.3). Illness rates increased directly with proximity of exposure to the index case. However, four of eight students who were in the same cubicle, but were not within 1 m of the index case-patient, contracted SARS. Proximity to the index case-patient was associated with transmission, which is consistent with droplet spread. Transmission through fomites or small aerosols cannot be ruled out.
Url:
DOI: 10.3201/eid1002.030452
PubMed: 15030696
PubMed Central: 3322939
Affiliations:
- Australie, République populaire de Chine, États-Unis
- Géorgie (États-Unis)
- Sha Tin
- Université chinoise de Hong Kong
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Parashar</name><affiliation wicri:level="2"><nlm:aff id="aff5">Centers for Disease Control and Prevention, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author></analytic><series><title level="j">Emerging Infectious Diseases</title><idno type="ISSN">1080-6040</idno><idno type="eISSN">1080-6059</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>We studied transmission patterns of severe acute respiratory syndrome (SARS) among medical students exposed exclusively to the first SARS patient in the Prince of Wales Hospital in Hong Kong, before his illness was recognized. We conducted a retrospective cohort study of 66 medical students who visited the index patient’s ward, including 16 students with SARS and 50 healthy students. The risk of contracting SARS was sevenfold greater among students who definitely visited the index case’s cubicle than in those who did not (10/27 [41%] versus 1/20 [5%], relative risk [RR] 7.4; 95% confidence interval [CI] 1.0 to 53.3). Illness rates increased directly with proximity of exposure to the index case. However, four of eight students who were in the same cubicle, but were not within 1 m of the index case-patient, contracted SARS. Proximity to the index case-patient was associated with transmission, which is consistent with droplet spread. Transmission through fomites or small aerosols cannot be ruled out.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Australie</li><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>Géorgie (États-Unis)</li></region><settlement><li>Sha Tin</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Wong, Tze Wai" sort="Wong, Tze Wai" uniqKey="Wong T" first="Tze-Wai" last="Wong">Tze-Wai Wong</name></noRegion><name sortKey="Chan, Paul K S" sort="Chan, Paul K S" uniqKey="Chan P" first="Paul K. S." last="Chan">Paul K. S. Chan</name><name sortKey="Lau, Joseph Tak Fai" sort="Lau, Joseph Tak Fai" uniqKey="Lau J" first="Joseph Tak-Fai" last="Lau">Joseph Tak-Fai Lau</name><name sortKey="Li, Yuguo" sort="Li, Yuguo" uniqKey="Li Y" first="Yuguo" last="Li">Yuguo Li</name><name sortKey="Lui, Siu Fai" sort="Lui, Siu Fai" uniqKey="Lui S" first="Siu-Fai" last="Lui">Siu-Fai Lui</name><name sortKey="Sung, Joseph J Y" sort="Sung, Joseph J Y" uniqKey="Sung J" first="Joseph J. Y." last="Sung">Joseph J. Y. Sung</name><name sortKey="Tam, Wilson" sort="Tam, Wilson" uniqKey="Tam W" first="Wilson" last="Tam">Wilson Tam</name><name sortKey="Yu, Tak Sun" sort="Yu, Tak Sun" uniqKey="Yu T" first="Tak-Sun" last="Yu">Tak-Sun Yu</name></country><country name="Australie"><noRegion><name sortKey="Lee, Chin Kei" sort="Lee, Chin Kei" uniqKey="Lee C" first="Chin-Kei" last="Lee">Chin-Kei Lee</name></noRegion></country><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Bresee, Joseph S" sort="Bresee, Joseph S" uniqKey="Bresee J" first="Joseph S." last="Bresee">Joseph S. Bresee</name></region><name sortKey="Parashar, Umesh D" sort="Parashar, Umesh D" uniqKey="Parashar U" first="Umesh D." last="Parashar">Umesh D. Parashar</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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